How GLP-1 Agonists Change the Skin: Explained by Dr. Sivamani, Integrative Dermatologist
Considering adding a GLP-1 or GIP medication to jump start your weight loss journey? These breakthrough medications can work miracles for those craving a reliable solution for weight loss. But there are side-effects you may not have considered.
GLP-1 medications like Ozempic can accelerate multiple signs of aging, particularly facial volume loss, often referred to as “Ozempic Face”. While not a medical condition, Ozempic Face is a common side-effect of GLP-1 medications for weight loss.
Facial changes with GLP-1 and GIP agonists
Already begun a weight loss regimen using on a GLP-1 or GIP agonist? If so, you may be noticing facial changes. The effects of facial volume loss may include: sagging skin, particularly in the cheeks and jawline, hollowness around the eyes, and a rapid loss of facial volume leading to a gaunt, aged appearance.
The Science of GLP-1 and GIP Agonists
To treat loss of facial volume and other signs of Ozempic Face, Image Skincare collaborated with Dr. Raja Sivamani, an Integrative Dermatologist and Adjunct Associate Professor of Dermatology at UC Davis.
Dr. Sivamani has identified multiple factors leading to facial volume loss when taking a GLP-1 or GIP agonist. While highly effective for weight loss, the medications “turn off” adipose-derived stem cells and can reduce production of collagen, elastin, and hyaluronic acid in the skin.
Importantly, the loss of connective tissue ranges from 25% to 39% of the total weight. The significant loss of fat, muscle, and connective tissue results in visibly sagging skin and deep folds at the mouth and jowls.
Our breakthrough approach to facial volume loss
Working with Dr. Sivamani, Image Skincare co-founder and plastic surgeon Dr. Marc Ronert created a breakthrough solution: VOL.U.LIFT™ GLP-1 4D Skin Rebound Complex. It's the first treatment developed for facial changes due to rapid weight loss when using GLP-1 agonists.
Introducing VOL.U.LIFT™ GLP-1 4D Skin Rebound Complex
VOL.U.LIFT™ GLP-1 4D Skin Rebound Complex is a revolutionary topical treatment that improves the appearance of facial skin in 4D: deflation, deep wrinkles, dehydration and density.
VOL.U.LIFT™ GLP-1 4D Skin Rebound Complex is a firming face cream designed with next generation hyaluronic acid, collagen fragments, bakuchiol and amino acids with lipofilling results. The complex of potent actives in our skin tightening crème improves skin impacted by GLP-1 induced facial volume loss and skin texture decline by addressing the appearance of lost volume, sagging, crepey skin texture, dehydration and wrinkles.
