Built on Science. Proven on Skin.
576+ Validated Studies
291
In-Vivo Efficacy Studies
119
Safety & Tolerance Studies
51
In-Vivo SPF Testing
46
Non-Comedogenic & Ophthalmological
49
In-Vitro UVA Testing
20
Ex-Vivo Studies
A comprehensive record of the efficacy and safety testing across our portfolio.
How IMAGE earns the word “clinical”
Medical-grade is not a label you print — it is a standard you meet. We meet it three ways, on every formula.
Physician-led Formulation
Every product is developed under our cofounder Dr. Marc Ronert, a European board-certified plastic surgeon — medical-grade actives at maximum allowable concentrations, engineered for measurable results, not marketing.
Independent Clinical Testing
Our formulas are put through clinical
evaluation using third-party testing to objectively measure product performance because proof is most credible when it comes from outside our own walls.
Medical & Peer Review
Our science is guided by our medical dermatologist advisor and published in the peer-reviewed literature — then proven daily by 60,000+ skincare professionals in 60+ countries.
THE MINDS BEHIND THE SCIENCE
Real Clinicians. Real Accountability.
IMAGE was founded by an aesthetician and a plastic surgeon, and our science is overseen by practicing medical experts.
Dr. Marc A. Ronert, M.D., Ph.D.
European board-certified plastic surgeon and Co-Founder and CEO of IMAGE Skincare. With decades of experience in aesthetic medicine, he guides the brand’s clinical and scientific approach, translating advances in skin science into clinically supported skincare solutions.
Dr. Raja Sivamani, MD, MS, AP
A board-certified dermatologist, bioengineer and Ayurvedic practitioner whose work bridges clinical dermatology, scientific research and integrative medicine. A widely published researcher with more than 195 peer-reviewed publications.
Dr. Lily Talakoub, MD, FAAD, DABOM
A board-certified dermatologist and founder of McLean Dermatology and Skincare Center and Potomac Dermatology and Skincare Center. Dr. Talakoub specializes in medical, surgical and cosmetic dermatology, with expertise in skin health and facial aesthetics.
Dr. med. Holger Hofheinz
A Board-certified specialist in Plastic and Aesthetic Surgery and Medical Director of Klinik am Rhein in Düsseldorf, Germany. In addition to his clinical practice, he is active in medical education, regularly lecturing and performing guest surgeries in Germany and internationally.
Dr. med. Edouard Manassa
A specialist in Plastic and Aesthetic Surgery based in Düsseldorf, Germany, with more than two decades of experience in aesthetic medicine and surgery. He's practiced at Klinik am Rhein since 2013 and is also co-founder of PAAU and the PAAU Academy, where he is actively involved in advancing physician education in aesthetic medicine.
CLINICALLY PROVEN
The Results, Measured.
VITAL C hydrating anti-aging serum
100%
agreed the product hydrates skin
AGELESS total pure hyaluronic 6 filler
97%
agreed their skin looks visibly smoother
the MAX neck lift
82%
noticed an improvement in the sagging of the jawline
VOL.U.LIFT GLP-1 4D skin rebound complex
23%
Increase in net elasticity.
Seeing is Believing: Before & Afters
22.5% increase in firmness
23.2% increase in net elasticity
*Based on an 12-week clinical study. See product page for details.
100% Agreed that skin is firmer and lifted
90% Reported that skin looks rejuvenated
*Based on an 8-week clinical study. See product page for details.
AGELESS+
Nightly Firming, Plumping, Standard Dose
- 1.7 oz
- .5 oz
93% Agreed that product was gentle on skin
80% Reported firmer skin
*Based on a 4-week clinical study. See product page for details.
93% Agreed the product improves skin tone
93% Reported that skin is more hydrated
*Based on a 4-week clinical study. See product page for details.
94% Reported product helps restore firmness & elasticity
89% Agreed that skin appears brighter
*Based on a 12-week clinical study. See product page for details.
- 1 fl oz
- 0.5 fl oz
92% Reported product minimizes appearance of redness
83% Reported the product improves skin's health
*Based on a 4-week clinical study. See product page for details.
XOSM® is a proprietary, patent-pending biomimetic delivery technology designed to optimize the delivery and penetration of powerful antioxidants into the epidermis. The key active complex contains 3 powerful bioactives encapsulated for precision delivery:
Astaxanthin-rich microalgae delivers exceptional antioxidant protection to help defend skin against oxidative stress and photo-damage from UV and blue light, while supporting skin’s natural antioxidant defenses.
Ectoin helps protect skin from environmental stressors, including UV, visible and blue light, pollution and heat, while supporting skin’s natural self-defense mechanisms for healthier-looking skin.
THD ascorbate is a highly stable, lipid-soluble form of vitamin C that absorbs efficiently to help defend against free radicals while improving the look of pigmentation and enhancing skin radiance.
XOSM In Action
Four collections. One clinically validated delivery system.
IMAGE MD®
Role of XOSM: Amplifies delivery of biotech-grade actives, including longevity peptides and barrier-repair complexes, deep into the epidermis, supporting structural skin resilience and advanced regenerative performance.
DAILY PREVENTION®
Role of XOSM: Enhances delivery of antioxidant actives beyond the stratum corneum, supporting reduction of UV-induced IL-6 and IL-8 while preserving collagen against MMP-9-driven degradation.
AGELESS+ retinol
Role of XOSM: Acts as a precision carrier for retinol and supporting actives, improving stability, reducing irritation potential, and ensuring targeted epidermal delivery for visible anti-aging results.
VOL.U.LIFT®
Role of XOSM: Drives the GLP-1 4D Skin Rebound Complex deeper into epidermal layers, maximizing bioavailability of volumizing and firming actives where skin density and elasticity are shaped.
PUBLISHED & PEER-REVIEWED
Our Science, In The Literature
Peer review is the highest bar in clinical credibility
A topical approach to GLP-1/GIP agonist-induced tissue changes in the face, neck and décolletage: a case series evaluation
Journal of Aesthetic Nursing 2026
Efficacy and tolerability of a high-concentration vitamin C serum in photoaged skin
Journal of Cosmetic Dermatology · 2024
Topical Volumizing Cream Improves Facial Volume and Skin Health in Adults With Rapid Weight Loss From Pharmacologic (GLP-1/GIP Agonists), Surgical, or Behavioral Interventions
Journal of Cosmetic Dermatology 2025
Inside the Formulas: What Makes it Medical-Grade
Maximum allowable concentrations
Actives dosed to the highest levels permitted for over-the-counter efficacy — the concentration that separates real results from a pleasant experience.
Clean clinical standards
Rigorous, results-first formulation without unnecessary chemicals — clean where it matters, clinical where it counts.
Optimized delivery systems
Encapsulation and vectorized delivery carry actives where they work, with the stability medical-grade formulation demands.
Professional-only integrity
Developed for, and dispensed through, trained professionals — the way medical-grade skincare is meant to be delivered.
Maximum allowable concentrations
Actives dosed to the highest levels permitted for over-the-counter efficacy — the concentration that separates real results from a pleasant experience.
Clean clinical standards
Rigorous, results-first formulation without unnecessary chemicals — clean where it matters, clinical where it counts.
Optimized delivery systems
Encapsulation and vectorized delivery carry actives where they work, with the stability medical-grade formulation demands.
Professional-only integrity
Developed for, and dispensed through, trained professionals — the way medical-grade skincare is meant to be delivered.
VOL.U.LIFT™ — science for how you live now





